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Research Scientist - In Vivo Pharmacology

Company: Scientific Search
Location: Avenel
Posted on: January 7, 2022

Job Description:

Be sure to check out all of our other current openings at www.scientificsearch.com

Our publicly traded Oncology focused biopharmaceutical client has tasked Scientific Search with finding a highly motivated Research Scientist to assist with in vivo pharmacology efforts in Oncology The successful candidate will possess hands-on experience in vivo pharmacology including cell culture handling and dosing laboratory mice/rats, and collection of a variety of tissues (e.g. blood, tumor etc) after euthanasia.

Responsibilities
In vitro cell culture of human and mouse cancer cell lines
Monitor daily animal health and welfare while performing daily animal health observations.
???????Ability to restrain, handle and manipulate mice and rats as assigned including dosing rodents by PO/IV/IP/SC routes. ???????
???????Independently execute in vivo pharmacology studies to demonstrate efficacy and characterize mechanism of action (PD/PK) of lead molecules in various rodent models of cancer.
Keeps accurate records and enters data into an electronic laboratory notebook in a timely manner.
Assists with routine husbandry tasks as needed.

Requirements
M.S. with minimum 1+ years, or B.S. with minimum 3+ years pharmaceutical industry experience executing in vivo pharmacology studies with immunocompetent and immunocompromised animals in oncology.
Experience using multiple types of in vivo oncology models (immunocompetent and immunocompromised mouse models, etc.)
Experience with genetically engineered mouse models (i.e. colony maintenance, breeding, weaning, PCR genotyping)
Superior technical expertise with standard in vivo techniques, including dosing and sampling routes (e.g., po, ip, sc, iv dosing; submandibul, retro-orbital, cardiac bleeds; necropsy and organ/tumor harvest) and tumor measurements is required.
Competency with mouse surgical techniques (orthotopic implants, etc.) will also be highly valued.
Expertise with the aseptic culture of mammalian cells (cell lines and primary cells), including propagating cultures and freezing cells.
Experience with ex vivo techniques and analysis (tissue extraction, single cell dissociation) will be highly valued.
Experience with IACUC and AAALAC.
Experience and proficiency in working with data/statistical analysis software packages such as GraphPad/Prism

For immediate consideration please email Kevin Wasser, at Kevin@Scientificsearch.com

Keywords: Scientific Search, Elizabeth , Research Scientist - In Vivo Pharmacology, Other , Avenel, New Jersey

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